Synthetic nanoparticles as carrier system offer significant opportunities in medicine by acting as vehicles to transport drugs through biological barriers. Both in diagnostics and in therapy, as future-oriented technology platforms, they open up new possibilities for the targeted and efficient treatment of cancer and cardiovascular diseases in particular. New treatment methods based on nanoparticles are conceivable, but their risks are yet to be fully evaluated. KIT scientific findings contribute to assessing the influence of the particles on living organisms. The digital event will feature expert presentations on two main topics, followed by lively discussions.
Nanoparticles for drug delivery
The research groups of Prof. Claus Feldmann (Karlsruhe Institute of Technology) and Prof. Frauke Alves (University Hospital Göttingen) start with the topic “nanoparticles for drug delivery”. In a collaboration, they have studied the delivery of glucocorticoids against inflammation using fluorescent hybrid nanoparticles (patented). The zirconium-based technology is synthesizable in water and has a very high drug loading of 70-85% per nanoparticle.
Biocompatibility of nanomaterials
Researchers Dr. Carsten Weiss and Sonja Mülhopt (both Karlsruhe Institute of Technology) will then introduce the topic of “biocompatibility of nanomaterials” in medicine based on their research. Although the benefits of nanoparticles are obvious, there is concern in society that the same properties that enable a variety of applications might also have adverse effects on the human body. This expert presentation will provide insight into research on the interaction of synthetic nanoparticles or nanostructured surfaces with living systems.
- 2:00 – 2:10 Welcome
- 2:10 – 2:25 Introduction
- 2:25 – 2:45 Topic 1: Nanoparticles for drug delivery | Prof. Claus Feldmann (KIT), Prof. Frauke Alves (University Göttingen)
- 2:45 – 3:00 Discussion on topic 1
- 3:00 – 3:15 Break (time for networking)
- 3:15 – 3:30 Topic 2: Biocompatibility of nanomaterials | Dr. Carsten Weiss (KIT), Sonja Mülhopt (KIT)
- 3:30 – 3:50 Panel talk: “Does the future of medication lie in nanovehicles?” with industry guests:
Dr. Roland Böttger (CureVac) and Dr. Danilo Maddalo (Genentech)
- 3:50 – 4:00 Closing and open networking